A TREATMENT FOR ADULTS WITH TYPE 2 DIABETES MELLITUS, IN ADDITION TO DIET AND EXERCISE
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Tablets shown are not actual sizes.
Tablets must be swallowed whole and not be split or cut.1
Assessment of renal function is recommended prior to initiation of ONGLYZA and periodically thereafter.1
When treating your patients with type 2 diabetes mellitus, consider ONGLYZA as an add-on to commonly used oral agents such as metformin to help your patients get where they need to be.
Drug Interactions
Strong CYP3A4/5 inhibitors (eg, ketoconazole): Coadministration with ONGLYZA significantly increases saxagliptin concentrations. Recommend limiting ONGLYZA dosage to 2.5 mg once daily.
Use in Specific Populations
In patients with moderate or severe renal impairment, or end-stage renal disease (eGFR <45 mL/min/1.73 m2), recommended dosage is 2.5 mg once daily regardless of meals. ONGLYZA should be administered following hemodialysis. Assess renal function before starting ONGLYZA and periodically thereafter.